Peroxiredoxins, gerontogenes linking aging to genome instability and cancer
نویسندگان
چکیده
منابع مشابه
Peroxiredoxins, gerontogenes linking aging to genome instability and cancer.
Age is the highest risk factor known for a large number of maladies, including cancers. However, it is unclear how aging mechanistically predisposes the organism to such diseases and which gene products are the primary targets of the aging process. Recent studies suggest that peroxiredoxins, antioxidant enzymes preventing tumor development, are targets of age-related deterioration and that bols...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2012
ISSN: 0890-9369
DOI: 10.1101/gad.200006.112